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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX1
All Species:
20
Human Site:
S519
Identified Species:
27.5
UniProt:
O43933
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43933
NP_000457.1
1283
142867
S519
D
K
N
I
F
L
L
S
P
N
L
L
Q
K
T
Chimpanzee
Pan troglodytes
XP_519198
1283
142803
S519
D
K
N
I
F
L
L
S
P
N
L
L
Q
K
T
Rhesus Macaque
Macaca mulatta
XP_001101055
1278
142022
S517
D
K
N
I
F
L
L
S
P
N
L
L
Q
K
T
Dog
Lupus familis
XP_532459
1267
140567
S503
K
E
N
I
F
L
L
S
T
N
L
L
R
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q5BL07
1284
141409
S520
G
K
T
V
F
V
L
S
S
I
L
L
Q
K
I
Rat
Rattus norvegicus
P46462
806
89330
I126
I
D
D
T
V
E
G
I
T
G
N
L
F
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520628
1178
126535
S484
E
E
S
V
Y
T
L
S
A
S
I
L
Q
E
T
Chicken
Gallus gallus
XP_418655
1290
143066
R527
L
S
P
S
L
L
Q
R
T
N
I
Q
V
L
L
Frog
Xenopus laevis
P23787
805
89193
G125
P
I
D
D
T
V
E
G
I
T
G
N
L
F
E
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
I126
I
D
D
T
V
E
G
I
T
G
N
L
F
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
E121
L
P
I
D
E
S
T
E
G
V
T
G
N
L
F
Honey Bee
Apis mellifera
XP_397107
1069
120490
D389
V
S
V
K
D
F
E
D
Y
V
K
K
Y
S
S
Nematode Worm
Caenorhab. elegans
P54812
810
89622
G130
P
I
D
D
T
I
E
G
L
T
G
N
L
F
D
Sea Urchin
Strong. purpuratus
XP_797089
1508
166130
L673
T
R
K
A
E
T
S
L
G
Q
K
P
K
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCN8
815
90322
I135
I
E
G
V
S
G
N
I
F
D
A
Y
L
K
P
Baker's Yeast
Sacchar. cerevisiae
P24004
1043
117258
P363
L
T
N
N
L
I
L
P
T
E
Q
I
I
I
E
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
M569
R
D
V
Q
S
A
V
M
A
G
L
K
H
Y
F
Conservation
Percent
Protein Identity:
100
99.6
92.8
86.4
N.A.
82
23.3
N.A.
52.4
62.4
22.9
22.8
N.A.
23.6
27.6
22.1
35.2
Protein Similarity:
100
100
94.9
92
N.A.
89.5
39.2
N.A.
66
77.6
38.6
39
N.A.
37.6
46.7
38.4
53.2
P-Site Identity:
100
100
100
73.3
N.A.
53.3
6.6
N.A.
33.3
13.3
0
6.6
N.A.
0
0
0
0
P-Site Similarity:
100
100
100
86.6
N.A.
66.6
20
N.A.
86.6
20
13.3
20
N.A.
0
6.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.7
21.4
Protein Similarity:
N.A.
N.A.
N.A.
38.5
45.2
40.9
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
6
0
6
0
0
12
0
6
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
18
18
24
18
6
0
0
6
0
6
0
0
0
0
6
% D
% Glu:
6
18
0
0
12
12
18
6
0
6
0
0
0
18
18
% E
% Phe:
0
0
0
0
30
6
0
0
6
0
0
0
12
12
12
% F
% Gly:
6
0
6
0
0
6
12
12
12
18
12
6
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% H
% Ile:
18
12
6
24
0
12
0
18
6
6
12
6
6
6
6
% I
% Lys:
6
24
6
6
0
0
0
0
0
0
12
12
6
36
0
% K
% Leu:
18
0
0
0
12
30
42
6
6
0
36
48
18
12
6
% L
% Met:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% M
% Asn:
0
0
30
6
0
0
6
0
0
30
12
12
6
0
0
% N
% Pro:
12
6
6
0
0
0
0
6
18
0
0
6
0
0
6
% P
% Gln:
0
0
0
6
0
0
6
0
0
6
6
6
30
0
0
% Q
% Arg:
6
6
0
0
0
0
0
6
0
0
0
0
6
6
0
% R
% Ser:
0
12
6
6
12
6
6
36
6
6
0
0
0
6
6
% S
% Thr:
6
6
6
12
12
12
6
0
30
12
6
0
0
0
30
% T
% Val:
6
0
12
18
12
12
6
0
0
12
0
0
6
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
6
0
0
0
6
0
0
6
6
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _